Product Name :
Mouse anti Human CD57
Description :
| Clone NK-1 | Isotype IgM | Product Type Monoclonal Antibody | Units 200 µg | Host Mouse | Species Reactivity Human | Application Immunofluorescence Immunohistochemistry Immunoprecipitation Western Blotting
Background :
Immunogen: Hybridoma produced from mice immunized with human peripheral blood mononuclear cells.
Source :
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity). Synonyms: HNK1, GLCATP, NK-1, HNK-1, LEU7, NK1, 151290, B3GAT1, Q9P2W7, GlcUAT-P, CD57, GlcUATP, GlcAT-P, 27087, NK 1, HNK 1, GlcAT P, GlcUAT P <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Protein A/G Chromatography Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Western blotting (1-10 µg/ml), Immunoprecipitation (1-2 µg per 100-500 µg of total protein), Immunofluorescence (2-20 µg/ml), Immunohistochemistry (2-20 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Human lymph node, Tonsil
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
Abo, T., et al. J. Immuno., 127, 1024 (1984)
Related websites: https://www.medchemexpress.com/antibodies.html
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