Product Name :
Rabbit anti Human Nucleolar Protein 4
Description :
| Isotype IgG | Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application ELISA Immunohistochemistry Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human NOL4 protein
Source :
Novel methylation target specific for cervical cancer. Could be a marker in the early detection, risk prediction and etiologic research of cervial cancer. While the biological role of NOL4 in cervical cancer has yet to be determined, it is possible that it could be a potential tumor suppressor gene. It also appears to have important roles in cell cycle and apoptosis as well as functioning in ribosomal transcription and subunit assembly. Synonyms: NOL4 <
Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Western blotting (1:400 dilution) and immunohistochemistry on paraffin embedded tissues (2 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Ueki, N., et al. ‘NOLP: identification of a novel human nucleolar protein and determination of sequence requirements for its nucleolar localization.’ Biochem Biophys Res Commun 1998;252:97-102. 2. Wang, S.S., et al. ‘Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanning.’ Cancer Res 2008;68:2489-2497. 3. Visintin R, et al. ‘The nucleolus: the magician’s hat for cell cycle tricks.’ Curr Opin Cell Biol 2000;12:372–7. 4. Olson MO, et al. ‘The nucleolus: an old factory with unexpected capabilities.’ Trends Cell Biol 2000;10:189–96.
Related websites: https://www.medchemexpress.com/antibodies.html
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