Product Name :
Rabbit anti Human Programmed cell death protein 1
Description :
| Isotype Ig | Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Immunohistochemistry Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human PD1 protein.
Source :
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors. Synonyms: CD279, PD1 <
Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for immunohistochemistry (2-4 µg/ml) and Western blotting (1-2 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Human kidney
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Shinohara, T., et al. ‘Structure and chromosomal localization of the human PD-1 gene (PDCD1)” Genomics, 23, 704-706 (1994)2. Fife, B.T., Pauken, K.E. ‘The role of the PD-1 pathway in autoimmunity and peripheral tolerance.” Ann. N.Y. Acad. Sci., 1217, 45-59 (2011)
Related websites: https://www.medchemexpress.com/antibodies.html
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