Product Name :
Rabbit anti Rat BAG-5
Description :
| Product Type Polyclonal Antibody | Units 100 µg | Host Rabbit | Species Reactivity Rat | Application Immunohistochemistry (paraffin) Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human BAG-5 protein.
Source :
It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70Õs anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization. <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration
Specificity :
Applications :
Anibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Takayama,S., et al. ‘An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.’ J. Biol. Chem. 1999, 274: 781-786
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
EGFR Antibody (YA775)
Rituximab (anti-CD20)
Alkaline Phosphatase Antibody: Alkaline Phosphatase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 57 kDa, targeting to Alkaline Phosphatase. It can be used for WB,ICC,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.