Product Name :
Sheep anti Avian TGF beta II receptor (77-148)

Description :
| Isotype IgG | Product Type Polyclonal Antibody | Units 100 µg | Host Sheep | Species Reactivity Avian | Application Immunohistochemistry Western Blotting

Background :
Immunogen: Protein containing chick transforming growth factor type II receptor a.a.77-148.

Source :
Epithelial-mesenchymal transformation is a critical event in the development of many organ systems including heart. Transforming Growth Factor (TGF ) is one of a number of factors that mediates this transformation.Antibodies directed against TGF Type II recepttor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion. Synonyms: TGBb Type II r; TGF beta II receptor; transforming growth factor receptor beta, Type II <

Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration

Specificity :

Applications :
Western Blot (1:100), Immunohistochemistry Functional Analysis: Immunohistochemistry Positive Control: Recombinant proteins conjugated to OVA, GST, His tags and other. Native TGF beta II proteins.

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Room Temperature

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1) C. Brown, et. al. (1999) Dev. Dynamics, 1-7

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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