Product Name :
4-Hydroxypropranolol hydrochloride
Description:
4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties.
CAS:
14133-90-5
Molecular Weight:
311.80
Formula:
C16H22ClNO3
Chemical Name:
4-2-hydroxy-3-[(propan-2-yl)amino]propoxynaphthalen-1-ol; chlorohydrogen
Smiles :
Cl.CC(C)NCC(O)COC1=CC=C(O)C2=CC=CC=C21
InChiKey:
ROUJENUXWIFONU-UHFFFAOYSA-N
InChi :
InChI=1S/C16H21NO3.ClH/c1-11(2)17-9-12(18)10-20-16-8-7-15(19)13-5-3-4-6-14(13)16;/h3-8,11-12,17-19H,9-10H2,1-2H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol.Iptacopan site 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties.|Product information|CAS Number: 14133-90-5|Molecular Weight: 311.80|Formula: C16H22ClNO3|Synonym:|(±)-4-hydroxy Propranolol hydrochloride|Chemical Name: 4-2-hydroxy-3-[(propan-2-yl)amino]propoxynaphthalen-1-ol; chlorohydrogen|Smiles: Cl.CC(C)NCC(O)COC1=CC=C(O)C2=CC=CC=C21|InChiKey: ROUJENUXWIFONU-UHFFFAOYSA-N|InChi: InChI=1S/C16H21NO3.ClH/c1-11(2)17-9-12(18)10-20-16-8-7-15(19)13-5-3-4-6-14(13)16;/h3-8,11-12,17-19H,9-10H2,1-2H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Piroxicam Autophagy |Shelf Life: ≥12 months if stored properly.PMID:32865111 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Fitzgerald JD, et al. Pharmacology of 4-hydroxypropranolol, a metabolite of propranolol. Br J Pharmacol. 1971 Sep;43(1):222-35.Nelson WL, et al. The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite. J Med Chem. 1984 Jul;27(7):857-61.Ivan Tong Mak, et al. Potent Antioxidant Properties of 4-Hydroxyl-propranolol. Journal of Pharmacology and Experimental Therapeutics. 2004, 308(1):85-90.Products are for research use only. Not for human use.|