Product Name :
Rabbit anti-NTCP Polyclonal Antibody
Synonym :
Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN
Host :
Rabbit
Species Reactivity:
Human
Specificity :
SLC10A1
Predicted Reactivity:
Mouse, Rat, Dog, Horse, Rabbit
Applications :
WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg /test ICC=1:100-500 IF=1:100-500
Immunogen:
KLH conjugated synthetic peptide derived from human NTCP:21-120/349
Concentration :
1mg/ml
Purification :
affinity purified by Protein A
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20 ° C for one yearAvoid repeated freeze/that cycles
Research areas :
Immunology Signal transduction Transporter
Background :
Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM]
UniProt :
Q14973
Additional information:
Product Details FAQ Citations(5) Video Pictures Documents |Overview |Synonym Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN |Host Rabbit |Specificity SLC10A1 |Species Reactivity Human |Predicted Reactivity Mouse, Rat, Dog, Horse, Rabbit |Applications WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg /test ICC=1:100-500 IF=1:100-500 |Immunogen KLH conjugated synthetic peptide derived from human NTCP:21-120/349 |Properties |Concentration 1mg/ml |Purification affinity purified by Protein A |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ° C for one yearAvoid repeated freeze/that cycles |Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |Research areas Immunology Signal transduction Transporter |Target |Background Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM] |Cellular localization Cell membrane; |UniProt Q14973 | Sample: K562 (human)cell Lysate at 40 ug Primary: Anti- SLC10A1 at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 48 kD| Blank control: 293T(blue).Primary Antibody:Rabbit Anti-SLC10A1 antibody, Dilution: 1μg in 100 1μL 1X PBS containing 0.5% BSA(green);Isotype Control Antibody: Rabbit IgG used under the same conditions );Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA. |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-NTCP Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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