Product Name :
Rabbit anti Human Lass4
Description :
| Product Type Polyclonal Antibody | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Western Blotting
Background :
Immunogen: Synthetic peptide derived from human Lass4 protein.
Source :
It is thought that Lass4 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner. <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Western blotting (1 mg/ml starting dilution). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Lung and embryo
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Min, J., et al. ‘(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1.’ Mol. Cancer Res. 2007, 5(8):801-812 2. Ruckhaberle, E., et al. ‘Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.’ Breast Cancer Res Treat. 2007 Dec 4 [Epub ahead of print]
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
8-OHdG (DNA/RNA Damage) Antibody
IRAK-1 Antibody
SUZ12 Antibody: SUZ12 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to SUZ12. It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.