Product Name :
Rabbit anti Human Monocarboxylate Transporter 3 (MCT3)
Description :
| Product Type Polyclonal Antibody | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Western Blotting
Background :
Immunogen: Synthetic peptide derived from MCT3 protein.
Source :
Monocarboxylate Transporter 3 (MCT3) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Synonyms: Solute carrier family 16 member 8; MCT3; SLC16A8 <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Western blotting (1-5 µg/ml starting dilution). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Retinal pigment epithelium
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Yoon, H., et al. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.; Genomics 60:366-370(1999). 2. Zhu, S., et al. ‘Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.’ Circulation. 2005 Aug 30;112(9):1353-61. 3. Philip, N.J., et al. ‘Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.’ Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1305-11.
Related websites: https://www.medchemexpress.com/antibodies.html
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