Product Name :
Rabbit anti Human NUMB

Description :
| Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Western Blotting

Background :
Immunogen: Synthetic peptide derived from human Numb protein

Source :
Implicated in the control of cell fate decisions during development. Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis. Synonyms: Protein S171; Protein numb homolog <

Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: Lot specific, see vial

Specificity :

Applications :
Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Protein found in brain, liver, testis and epithelium

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1. Susini, L., et al. ‘Siah-1 binds and regulates the function of Numb.; Proc. Natl. Acad. Sci. U.S.A. 98:15067-15072(2001). 2. Verdi, J.M., et al. ‘Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage.; Proc. Natl. Acad. Sci. U.S.A. 96:10472-10476(1999).

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
FEN1 Antibody (YA765)
Sonelokimab
JNK1+JNK3 Antibody: JNK1+JNK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48/53 kDa, targeting to JNK1+JNK3. It can be used for WB,IP assays with tag free, in the background of Mouse, Rat.