Product Name :
Rabbit anti Human SALL4
Description :
| Isotype Ig | Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Immunohistochemistry Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human SALL4 protein
Source :
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. Synonyms: Sal-like protein 4, Zinc finger protein 797, Zinc finger protein SALL4 <
Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Immunohistochemistry (2-4 µg/ml) and Western blotting (1-2 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Human testis
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Ma, Y., et al. ‘SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice.’ Blood, 108, 2726-2735 (2006)2. Kohlhase, J., et al. ‘Okihiro syndrome is caused by SALL4 mutations.’ Hum. Mol. Genet., 11, 2979-2987 (2002)3. Yang, F., et al. ‘Sumoylation is important for stability, subcellular localization, and transcriptional activity of SALL4, an essential stem cell transcription factor.’ J. Biol. Chem., 287, 38600-38608 (2012)
Related websites: https://www.medchemexpress.com/antibodies.html
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