Product Name :
Rabbit anti Rat Kv1.4 Potassium Channel

Description :
| Isotype IgG | Product Type Polyclonal Antibody | Units 100 µg | Host Rabbit | Species Reactivity Rat | Application Western Blotting

Background :
Rabbits were immunized with a peptide derived from rat Kv1.4 potassium channel protein, conjugated to KLH

Source :
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential (1). Potassium channels are encoded by numerous genes whose products can be classified into distinct subfamilies. The most distinctively characterized is that of the Kv1 shaker class (2). Synonyms: Rabbit anti Kv1.4 Potassium Channel <

Product :
Provided as solution in phosphate buffered saline with 0.08% sodium azide Product Form: Unconjugated Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration

Specificity :
Species Reactivity: The rabbit anti kv 1.4 ptassium channel antibody recognizes a 90 kDa protein by western blot on rat hippocampal membranes and a protein of 76 kDa in lysates of HEK293 cells (3).

Applications :
Applications: 1- 10 ug/ml for western blot analysis, immunofluorescence, immunoprecipitation. Functional Analysis: Western Blotting

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature.

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1) Miller C. Science 1991: 252;1092-1096 2) Chandy K.G. et al. Handbook of receptors and channels. CRC Press 1995; 1-71. 3) Jugloff J.G.M. et al. J. Biol. Chem. 2000: 275; 1357-1364.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Ansuvimab
Sacituzumab
ATRX Antibody: ATRX Antibody is a non-conjugated and Mouse origined monoclonal antibody about 280 kDa, targeting to ATRX. It can be used for ICC,IHC-P assays with tag free, in the background of Mouse.