Product Name :
Sheep anti EBNA 3C

Description :
| Product Type Polyclonal Antibody | Units 250 µg | Host Sheep | Species Reactivity Virus | Application ELISA Immunoblotting Immunocytochemistry,Immunohistochemistry (frozen),(In)direct immunofluorescence. Western Blotting

Background :
Sheep were immunized with recombinant EBNA-3C protein

Source :
EBNA 3C is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines and is essential for EBV mediated transformation of these cell lines. This viral nuclear protein is essential for EBV mediated positive immunoblastic lymphomas, and functions as a transcription factor. Synonyms: EBNA 3C; Epstein-Barr Virus Nuclear antigen 6 <

Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration

Specificity :

Applications :
Applications: Immunoblotting – immunoprecipitates EBNA-3C when used at a dilution of 1:200 (see reference). Functional Analysis: Immunoprecipitation

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
Sungwook Lee, Shuhei Sakakibara, Seiji Maruo, Bo Zhao, Michael A. Calderwood, Amy M. Holthaus, Chiou-Yan Lai, Kenzo Takada, Elliott Kieff, and Eric Johannsen. Epstein-Barr Virus Nuclear Protein 3C Domains Necessary for Lymphoblastoid Cell Growth: Interaction with RBP-J Regulates TCL1. JOURNAL OF VIROLOGY (2009) 83, 12368–12377. doi:10.1128/JVI.01403

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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