Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed beneath the terms in the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution of the operate without having further permission supplied the original function is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).2 water content material, volume, or Title Loaded From File frequency of stools.11 A decrease in consistency (ie, soft or liquid) and a rise in the frequency of bowel movements to three stools per day have frequently been employed as a definition for epidemiological investigations. Based on a community-based study point of view, diarrhea is defined as a minimum of three or far more loose stools within a 24-hour period.12 A diarrheal episode is regarded as because the passage of 3 or much more loose or liquid stools in 24 hours before presentation for care, which can be deemed probably the most practicable in children and adults.13 Having said that, prolonged and persistent diarrhea can last involving 7 and 13 days and at least 14 days, respectively.14,15 The disease is hugely sensitive to climate, showing seasonal variations in numerous sites.16 The climate sensitivity of diarrheal illness is consistent with observations in the direct effects of climate variables on the causative agents. Temperature and Title Loaded From File relative humidity possess a direct influence around the price of replication of bacterial and protozoan pathogens and on the survival of enteroviruses inside the atmosphere.17 Overall health care journal.pone.0169185 seeking is recognized to be a result of a complicated behavioral course of action that is influenced by a number of elements, like socioeconomic and demographic and characteristics, perceived want, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed below the terms on the Inventive Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution with the function with out further permission provided the original function is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content material, volume, or frequency of stools.11 A lower in consistency (ie, soft or liquid) and a rise in the frequency of bowel movements to 3 stools per day have normally been utilised as a definition for epidemiological investigations. Depending on a community-based study point of view, diarrhea is defined as at the very least three or extra loose stools within a 24-hour period.12 A diarrheal episode is deemed because the passage of 3 or much more loose or liquid stools in 24 hours before presentation for care, which is considered one of the most practicable in kids and adults.13 Even so, prolonged and persistent diarrhea can last among 7 and 13 days and no less than 14 days, respectively.14,15 The illness is hugely sensitive to climate, displaying seasonal variations in numerous sites.16 The climate sensitivity of diarrheal illness is constant with observations in the direct effects of climate variables on the causative agents. Temperature and relative humidity have a direct influence on the price of replication of bacterial and protozoan pathogens and on the survival of enteroviruses within the environment.17 Well being care journal.pone.0169185 in search of is recognized to become a result of a complex behavioral course of action which is influenced by numerous variables, such as socioeconomic and demographic and characteristics, perceived require, accessibility, and service availability.