This implies that exogenous GABA therapy negates the requirement for N-sort Ca2+ channel-dependent endogenous GABA launch [35] and that in the absence of any endogenous GABA signaling (bicuculline), immediate activation of L-kind Ca2+ channels is sufficient to boost neuronal excitability for the duration of differentiation
In addition, the activation/ inactivation characteristics of the Na+ currents had been not affected by ACM (Figure 3B), implying that ACM did not modify the ratio of various Na+ channel…